Clinical Data & Operations Integrity

Velocity. Validity. Value.

ALCOA+ Standards ICH-GCP Compliance Risk Governance
⚙️

Clinical Ops Audit

Focus: Workflow Friction.

We analyze operational bottlenecks in study startup and maintenance to mitigate timeline risks.

🛡️

eTMF Audit

Focus: Inspection Readiness.

Ensuring your Trial Master File is not just a storage bin, but a structured asset that withstands scrutiny.

💾

Data Transfer Audit

Focus: Migration Physics.

Validating technical fidelity during migrations to prevent entropy, corruption, and data loss.

The Cost of Friction

Time is the single most expensive variable in clinical trials. Our Clinical Operations Audit identifies "dead air"—the unseen lag time between operational steps. We compare your cycle times against industry best-practice benchmarks to reveal where value leaks out of the system.

Audit Insight:

Most delays don't happen during tasks, but in the handoffs between them. We identify and compress these gaps.

Days to Site Activation (Benchmark vs. Actual)

The Inspection Gap

Visualizing the delta between "Expected Documents" (Milestone based) and "Actual Filed Documents."

eTMF Health

A trial without a pristine story is a liability. If the "Actual" line lags the "Expected" line, you are accumulating Regulatory Debt.

The "Panic Gap"

The divergence at Month 6 (shown left) represents thousands of unfiled documents that trigger pre-inspection chaos.

Data Entropy

Moving data introduces chaos. Whether integrating a merger or migrating legacy systems, we validate the technical fidelity of every byte. Our Data Transfer Audit looks beyond simple row counts to verify semantic integrity.

  • Clean Transfer: Semantic meaning preserved.
  • Transformation Error: Date formats, unit conversions, truncated text.
  • Data Loss: Dropped records or corrupted foreign keys.

Migration Fidelity Analysis

The TBM Perspective: Cost of Quality

Applying the 1-10-100 Rule to Clinical Data. The cost to fix a data error increases exponentially the longer it remains undetected.

*Bubble size indicates Financial Impact on the study budget.